Abstract: Supersymmetric Grand Unification scenarios with non-universal gaugino masses have been widely investigated in the context of the SU(5) and SO(10) gauge groups. Here, we take a less conventional approach, and revisit a class of orbifold models with non-universal gauginos, developed by Brignole, Ibáñez and Muñoz. We explore two distinct regions where supersymmetry breaking is either dilaton dominated, BIM-OI model, or moduli dominated, BIM-OII model. We then use the full trilinear couplings, gaugino and scalar masses boundary conditions predicted by such scenarios, confronting them with low energy constraints, including the Higgs boson mass and the Dark Matter relic density. We find plenty of viable scenarios which evade all experimental constraints as well as predicting the preferred Dark Matter abundance. We finally present benchmarks that should be explored at the LHC and future colliders.